Genetically engineered yeast produces THC and CBD - No plants required

09/15/2015 - 00:27

Roxanne Khamsi


In August, researchers announced they had genetically engineered yeast to produce the powerful painkiller hydrocodone. Now comes the perhaps inevitable sequel: Scientists have created yeasts that can make important constituents of marijuana, including the main psychoactive compound, tetrahydrocannabinol, or THC.

Synthetic versions of THC are available in pill form under brand names like Marinol and Cesamet; they are generally used to treat nausea, vomiting and loss of appetite caused by H.I.V.

READ MORE ON THE NEW YORK TIMES

Ref: Production of Δ9-tetrahydrocannabinolic acid from cannabigerolic acid by whole cells of Pichia (Komagataella) pastoris expressing Δ9-tetrahydrocannabinolic acid synthase from Cannabis sativa l. Biotechnology Letters (2015) | DOI: 10.​1007/​s10529-015-1853-x